To put out of proper order
To break up the order or progress of
It wasn't like Alex to let anger disrupt his schedule.
You can't just march into a person's life and disrupt it.
Prosperity requires civil liberties, prosperity thrives under lower taxes, and prosperity shrivels as wars disrupt the free flow of labor and capital.
A curse on you who disrupt the master's plans; you will pay dearly when the time of reckoning finally arrives!
Pierce had no scruples against slavery, and opposed anti-slavery agitation as tending to disrupt the Union.