To reduce life or the evidence of life
blunt, impair, dull, numb, desensitize, repress, slow, paralyze, anesthetize, drug, chloroform, gas, freeze, narcotize, etherize, put to sleep, make unfit, knock out, daze, benumb, incapacitate, depress, stupefy, stun, smother, stifle, suppress, frustrate, weaken, devitalize, injure, exhaust, tire, retard, knock stiff*, KO*, lay out*, dope*, put out of order*, take the edge off*; see also drug, weaken 2.
Antonyms animate*, revitalize, invigorate.