Surgery done to move the testis into the scrotum does not reduce the likelihood of malignancy but allows accessibility of the testes to screen for masses which will allow early treatment.
They can infiltrate nearby tissues, enter the bloodstream, and metastasize to bones, tissues, and organs far from the original malignancy.
Physical examination and routine x rays may yield enough evidence to diagnose benign bone tumors, but removal of tumor tissue for microscopic analysis (biopsy) is the only sure way to rule out malignancy.
Normocytic anemia may be caused by decreased production (e.g. malignancy and other causes of bone marrow failure), increased destruction (hemolytic anemia), or blood loss.
Most commonly the term refers to the collection and analysis of tissue from a suspected tumor to establish malignancy.