Synonyms for complicate

involve, convolute, confound, make difficult, make complex, make intricate, tangle, twist, snarl up, entangle, embroil, obscure, make multiform, make various, muddle, confuse, mix up, elaborate, embellish, compound, implicate, conceal, impede, perplex, vex, hinder, hamper, encumber, bedevil, darken, obfuscate, mystify, render unintelligible, jumble, knot, tie in knots, clog, ball up*; see also confuse, entangle.

Antonyms simplify*, clear up, disentangle.