That which produces such suffering; trouble, loss, affliction, etc.
Complete loss of hope.
The definition of anguish is a feeling of physical or mental pain.
A feeling of sorrow, disappointment, distress, or remorse about something that one wishes could be different.
(Dial.) A pain (in some part of the body)
(Informal) A source of annoyance; a nuisance:
A sudden sharp feeling of emotional distress:
Any of various other plants having similar foliage, such as meadow rue.
Mental anguish or pain caused by loss or despair
Find another word for heartache. In this page you can discover 14 synonyms, antonyms, idiomatic expressions, and related words for heartache, like: sorrow, despair, anguish, grief, regret, misery, pain, pang, rue, sadness and woe.