Mental anguish or pain caused by loss or despair
Men are heartache and more trouble than they're worth.
Nothing but heartache could come of it.
She certainly had seen her share of heartache, but unlike Jackson, she did believe it to be worth it.
I have seen her through some pretty nasty heartache, but honestly, I'm not confident she could survive losing you, and now she won't have to.
He had risen to fear, heartache, anxiety, bliss, pain and a hundred other feelings that made you beg to be able to bury your head beneath the covers and stay in the warm cocoon of sleep forever.