In 1777 Edward, the ninth of the Howard dukes, died childless in his ninety-second year.
His Irish title descended to his brother William, the general, who died childless in 1814.
Dean was childless but Cynthia was mother to a twenty-year-old college student.
Dying childless, the house of Valois-Angouleme followed from Francis I.
He there received the imperial crown, and summoned the Italian princes for a settlement of all disputed claims. Francesco Sforza, the last and childless heir of the ducal house, was left in Milan till his death, which happened in 1535.