Having a formal education
learned, trained, accomplished, skilled, literate, well-read, well-taught, informed, knowledgeable, scientific, scholarly, lettered, literary, intelligent, well-informed, well-versed, well-grounded, erudite, developed, formed, disciplined, shaped, prepared, instructed, civilized, fitted, versed in, informed in, acquainted with, nurtured, corrected, enriched, professional, expert, polished, cultured, finished, initiated, enlightened, tutored, schooled, book-learned, bookish, bluestocking(ed)*, highbrow*, up on*.
Antonyms illiterate, ignorant*, unlettered*.