Substance P Nerves from nociceptors use this peptide to activate relay neurons in the spinal cord.
Activity dependent excitability changes of nociceptors and mechanoreceptors Sensory neurons of the dorsal root ganglion are functionally heterogeneous.
As a group, these pain-sensing neurons are called nociceptors, and virtually every surface and organ of the body is wired with them.
Nociceptors are classified according to the stimulus that prompts them to transmit a pain signal.
Thermoreceptive nociceptors are stimulated by temperatures that are potentially tissue damaging.