To work like a slave; drudge
To work hard; exert oneself to get or do something; strive
To diminish the energy or strength; fatigue:
Find another word for knock-oneself-out. In this page you can discover 6 synonyms, antonyms, idiomatic expressions, and related words for knock-oneself-out, like: slave, labor, do-one-s-utmost, exhaust oneself, tire and work.