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Obviously their selection must be compatible with the maintenance of antigen binding in the final humanized monoclonal antibody.
This can be as easily achieved with chimaeric as with fully humanized or reshaped antibodies.
Globalization cannot be wrestled away from its creators and in the process humanized for those it presently terrorizes.
A humanized Mab used to treat colon cancer caused 17 percent of the cancer patients to experience adverse immune events  .
A population of rat hybridoma cells were transfected with an expression plasmid encoding a humanized monoclonal antibody.