Twisting of any portion of the intestines may cut off the supply of blood to a loop of bowel (strangulation), reducing the flow of oxygen to bowel tissue (ischemia) and leading to tissue death (gangrene).
Louis Pasteur first observed garlic's antibacterial qualities in 1858, and until World War II is was routinely used to prevent gangrene in patients with infected wounds.
Strangulation occurs in about 25 percent of bowel obstruction cases and is a serious condition that can progress to gangrene within six to 12 hours.
If malrotation or duodenal volvulus has caused the blood supply to be cut off in a portion of the intestine before surgery, death of intestinal tissue can result and life-threatening gangrene can develop.
He died of gangrene of the leg in his seventieth year.