Synonyms for strangeness

newness, unfamiliarity, exoticism, novelty, abnormality, singularity, eccentricity, fantasticality, weirdness, remoteness, indescribability, esotericism, esoterism, sense of being alien, unaccustomed quality, strange nature, unfamiliar surroundings, feeling of newness.

Antonyms familiarity*, acquaintanceship, homelike quality.