mutability, uncertainty, alteration, difficulty; see change 2. See syn. study at difficulty.
"vicissitude." YourDictionary, n.d. Web. 05 December 2018. <https://thesaurus.yourdictionary.com/vicissitude>.
vicissitude. (n.d.). Retrieved December 05th, 2018, from https://thesaurus.yourdictionary.com/vicissitude
Something that obstructs progress and requires great effort to overcome.
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