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The bursting of several of these altered cells is the method by which the skin vesicles are formed in certain conditions.
A viral culture swab from the vesicles will confirm the infection and then either topical or systemic acyclovir will be used as treatment.
Cytosolic entry of bisphosphonate drugs requires acidification of vesicles after fluid-phase endocytosis.
This calcium entry then triggers exocytosis of the presynaptic vesicles.
It is probable that most other membrane-bound organelles are ultimately derived from such vesicles.