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It triggers your house's fire system if it detects it has caught on fire.
In the case of a muscle cell, depolarisation triggers muscle contraction.
Sunlight triggers oxidative damage in the eye, which in turn can cause macular degeneration.
Other triggers cab be changes in host defenses e.g. friction during sexual intercourse inflaming the mucous membranes.
Now it comes to pass that the factory is unwilling to put triggers like that on guns to be sold over-the-counter.