Ancient scepticism was frankly opposed to religious belief.
But more important was the influence of philosophy, which led soon enough to a general scepticism among the upper classes.
But scepticism of this kind was not universal.
The doubts thus cast upon the age when the Homeric poems first assumed the fixed form of writing were closely associated with the universal scepticism as to the historical accuracy of any traditions whatever regarding the early history of Greece.
The extremest form of antagonism is pure scepticism or pure agnosticism, the assertion that nothing can be known.