The three polymorphisms studied were found to be in strong linkage disequilibrium.
In addition, approximately 2.5 single nucleotide polymorphisms were identified.
This is how single-nucleotide polymorphisms influence drug response patterns.
We genotyped the IVS1-397 and TA n microsatellite polymorphisms of the ESR1 gene in 325 cases and 327 controls samples of Hong Kong Chinese.
First, restriction fragment length polymorphisms (RFLPs) were established by Southern blot analysis.