Alexander the Great conceived the idea of restoring the Greek city; the two Nemeses who were worshipped at Smyrna are said to have suggested the idea to him in a dream.
Drome Racers utilizes cars based on the Construction series and Lego Racers 1 and 2 showcase traditional Lego cars and has you racing through different circuits against different nemeses.
Free radicals are nemeses we all have to deal with, whether we're aware of them or not.