The effect of human cytomegalovirus infection on the cell cycle of terminally differentiated myeloid cells.
They are also expressed on cells of the immune system, notably lymphoid and myeloid line.g. cells (e.g. erythrocytes ).
No increased incidence was found for acute myeloid leukemia or brain cancer which were of interest a priori based on earlier studies.
These myeloid malignancies result from transformation of an HSC and are associated with expansion of one or more haematopoietic lineages.
Our results are in keeping with the assumption that generalization, indicated by myeloid metaplasia, has a prodigious impact on prognosis in IMF.