Hippocampal atrophy is usually the most common finding in patients with temporal lobe epilepsy who are surgically treated.
The dentate gyrus of the hippocampal formation continues to generate new neurons well into adulthood.
In contrast, hippocampal interneurons recorded during gamma fire in phase with pyramidal cells [1] .
We focus on the hippocampal circuitry, but have recently strayed into developing neocortex to see whether similar principles apply there.
Surgery to remove the source of seizures in the hippocampus can cure temporal lobe epilepsy in patients with hippocampal sclerosis.