One research group had provided some in vitro data to suggest that induction of CYP2E1 resulted in 2,3-DCP mediated hepatotoxicity and glutathione depletion.
N-acetylcysteine (NAC) - an amino acid that naturally stimulates your body to produce glutathione - is a powerful antioxidant enzyme.
Selenium, itself an antioxidant, is required to activate one of the most important antioxidants found in the body, called glutathione.
Some of these metabolites are reactive and bind to various components of cells including glutathione and macro-molecules.
Drug transport is dependent on the presence of reduced glutathione.