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Conventional tillage, which depletes soil organic matter and creates the conditions for erosion is a major cause.
Iron is especially important for females around the time of menstruation as the process depletes the body of iron.
This is in part because the effort required by the body to process animal fats and products depletes you of both nutrients and energy.
One is the Blood shield, which depletes as you get hit.
You have an adrenaline meter that depletes, but you can fill it back up with power-ups and stalking prey.