Care should be used in combining SSRIs with major or minor tranquilizers or with anti-epileptic agents such as phenytoin (Dilantin) or carbamazepine (Tegretol).
Targets include other AEDs, particularly phenytoin, phenobarbitone, carbamazepine epoxide, and lamotrigine.
Are you taking carbamazepine (used to treat epilepsy or facial neuralgia - severe pain attacks in the face )?
Practice point Carbamazepine may occasionally cause leucopenia and other disorders including thrombocytopenia.
For severe depression that does not respond well to antidepressant, mood stabilizer drugs (e.g., lithium, carbamazepine, valproic acid) may be recommended.