On the heart and circulation the effects are stimulant unless large doses are given, when the pulse becomes slow and blood-pressure much lessened.
The blood-pressure synchronously falls, and the heart is arrested in diastole.
The individual muscle-fibres contract and expand more perfectly, and thus the diastole and systole of the heart are rendered more complete, the pulse is slowed, and the blood-pressure is raised.
Persons who have followed the diet have reported changes in blood-pressure, blood-sugar/insulin levels, and depression, all of which required alteration of their normal dose of medication for these conditions.
It is the principal blood-pressure raising hormone and a bronchial and intestinal smooth muscles relaxant.