Her chief benefactions were made to the hospital of St Katharine's by the Tower, London.
He left considerable benefactions to Pembroke Hall, Cambridge, Queen's College, Oxford, and Christ's College, Cambridge; he also endowed a free school at St Bees, and left money for the poor of St Bees, Canterbury, Lambeth and Croydon.
The latter's son Henry (1746-1812) became 3rd duke, and in 1810 succeeded also, on the death of William Douglas, 4th duke of Queensberry, to that dukedom as well as its estates and other honours, according to the entail executed by his own great-grandfather, the 2nd duke of Queensberry, in 1706; he married the duke of Montagu's daughter, and was famous for his generosity and benefactions.
Among the first of these benefactions was the great gymnasium of Ptolemy, built in the neighbourhood of the Agora about 250 B.C. Successive princes of the dynasty of Pergamum interested themselves in the adorn western entrance being the well-known Doric portico of Athena Archegetis with an inscription recording its erection from donations of Julius Caesar and Augustus.
His love for Cambridge never waned, and his own benefactions took the form of scholarships, fellowships and lectures.