The only mode of combating the malady seems to be to uproot the plants and burn them.
In September of the same year his physical malady reached a crisis, from which he emerged a helpless wreck, with faculties paralysed rather than destroyed - "He never talked nonsense or said a foolish thing."
But at times in history, left-handedness was thought to be a malady in need of curing (and in some parts of the world still is).
The same year symptoms of a fatal malady appeared, and death followed on the 8th of February 1874.
In 1872 grief for the death of his mother occasioned a mental malady, which led to the resignation of his professorship. After his complete and permanent recovery he built himself a villa on the bank of his native river, the Astichello, and lived there in tranquillity until his death on the 17th of May 1888.