Synonyms for headache

noun

1. A pain in the head

   migraine, sick headache, bilious headache, neuralgia, organic headache, megrim, cephalalgia, hemialgia, hemicrania, reflex headache, head-on*, big head*; see also pain 2.

2. *A source of vexation and difficulty

   problem, jumble, mess; see difficulty 1, 2, trouble 2.