In 1841-1843 he was in Europe on behalf of the Tyler administration, and he is said to have been instrumental in causing the appointment of Lord Ashburton to negotiate in Washington concerning the boundary dispute between Maine and Canada.
See Moses Coit Tyler, Patrick Henry (Boston, 1887; new ed., 1899), and William Wirt Henry (Patrick Henry's grandson), Patrick Henry: Life, Correspondence and Speeches (New York, 1890-1891); these supersede the very unsatisfactory biography by William Wirt, Sketches of the Life and Character of Patrick Henry (Philadelphia, 1817).
John Tyler, who succeeded to the presidency, was soon "read out of his party," and all his cabinet except Webster resigned.
He refused, for a time, to be driven, but because of their continued attacks, together with his ambition to become president, and because Tyler favoured the annexation of Texas while he was opposed to it, he resigned in May 1843.
He was forgiven by his party in the following year, but not until the opposition, provoked by the retention of his position under Tyler, had ruined whatever This case grew out of the Canadian rebellion of 1837.