Research on human tissues has confirmed that people of all genetic types can have the rogue prion protein responsible for the disease.
In historic times it was situate on the lower slopes of the hills, Coressus and Prion, which rise out of a fertile plain near the mouth of the river Cayster, while the temple and precinct of Artemis or Diana, to the fame of which the town owed much of its celebrity, were in the plain itself, E.N.E.
Besides these excavated monuments, the Stadion; the enceinte of fortifications erected by Lysimachus, which runs from the tower called the "Prison of St Paul" and right along the crests of the Bulbul (Prion) and Panajir hills; the round monument miscalled the "Tomb of St Luke"; and the Opistholeprian gymnasium near the Magnesian gate, are worthy of attention.
This is the change in conformation that is associated with protease resistance and the accumulation of insoluble aggregates of prion protein.
Research The abnormal prion protein causing vCJD remains a scientific enigma.