In Ireland Elizabeth miscarries again, and is generally maltreated by her mother-in-law.
Sometimes, only one fetus miscarries and there are no problems carrying the rest to term.
It can escalate into full labor-like symptoms depending on the stage of pregnancy during which one miscarries.
The husband eventually takes his own life. Meredith must operate on Owen while Cristina operates on Derek. Meredith miscarries while performing surgery.