There was no significant difference between groups in MMH or in the response to acetylcholine iontophoresis.
Weak evidence suggests that vincristine iontophoresis may have some benefit, but side effects are unpleasant.
Iontophoresis, which involves the application of an electrical current across the skin, can be used to treat plantar and palmar hyperhidrosis but requires daily treatment for about 30 minutes, often multiple times daily.
For palmar and plantar hyperhidrosis, topical treatment and iontophoresis, followed by Botox are recommended.
The sweat test uses a process called iontophoresis.