In most cases, 1 or more female donors had positive HLA and/or granulocyte antibodies.
Investigations The serum will be investigated by the indirect granulocyte immunofluorescence and chemiluminescence tests using donor granulocytes typed for HNA-1, -2 and -3.
This can be achieved by typing the patient for the relevant antigen and/or performing a direct granulocyte immunofluorescence test.
Please phone the granulocyte immunology laboratory to discuss these cases in advance.
The cells were collected after the daughter was given granulocyte macrophage colony stimulating factor for 5 days to boost her white blood cells.