When someone has depression along with periods of previous or current mania than the individual is diagnosed with bipolar disorder or manic depressive disorder.
A 2003 study found that the risk of suicide from death is about two and one half times higher in people with bipolar disorder taking divalproex than those taking lithium.
Some researchers have hypothesized that the use of antidepressants for depression may even trigger bipolar disorder in children who are genetically predisposed.
The trial was of four months duration and compared omega-3 fatty acids versus olive oil in 30 patients with bipolar disorder.
People with bipolar disorder should avoid supplements containing vanadium until more is known.