His successor was Adrian VI.
Some of the nominations were excellent, such as Lorenzo Campeggio, Giambattista Pallavicini, Adrian of Utrecht, Cajetan, Cristoforo Numai and Egidio Canisio.
The gates of Rome itself were shut against Frederick; and even on this first occasion his good understanding with Adrian began to suffer.
Byron's description, "[The] immemorial wood Rooted where once the Adrian wave flowed o'er," is probably true; but there is no evidence that it was in historic time that this change took place.
Before the completion of the Miami & Erie Canal to Toledo, the building of railways was begun in this region, and in 1836 a railway was completed from that city to Adrian, Michigan.