This leaves a gray zone of serologic testing for the core vaccines of canine distemper and canine parvovirus as well as canine adenovirus.
This means that an enormous number of normal adenovirus must be used for each clinical treatment, to overcome neutralization.
In a replication-defective adenovirus, the E1 region can be replaced with the transgene that is to be expressed.
To provide for efficient delivery of the cytokine, adenovirus vectors have been proposed to deliver the cytokine genes to the chicken.
The study product is an adenovirus derived vector which contains the gene for the enzyme thymidine kinase (TK ).