In 2005, Jessica Alba portrayed Sue Storm in the big screen adaption and again in the sequel.
In some cases two or more are required to make the adaption.
La Fea mas Bella (a Mexican telenovela and adaption of Yo Soy Betty la Fea) is one such program.
The Mists of Avalon - In this adaption of the Marion Zimmer Bradley novels, Merlin is the title of Taliesin, the Archdruid of Britain.
Her history was altered for the big screen adaption where she crossed paths with Wolverine in Canada and was later rescued by the X-Men from Sabretooth's attack.