Izzie, meanwhile, is having trouble with her patient, who needs a biopsy on a potentially cancerous testicular lump.
From time immemorial thera- savages have been accustomed to eat the hearts of lions and other wild animals, under the belief that they will thereby obtain courage and strength like that of the animal from which the heart had been taken, but in 1889 BrownSequard proposed to use testicular juice as a general tonic and stimulant.
The first scientific attempt to employ portions of raw organs in the treatment of disease was made by Lauder Brunton in diabetes in 1873, sixteen years before Brown-Sequard's paper on the effect of testicular juice.
A genetic male will have female genitalia as a result of the deficient testicular androgens.
However, in the case of testicular tumors, a small secondary hydrocele is present in one third of cases.