It has been suggested that synapsis may be connected with the early longitudinal splitting of the thread or with the pairing of the chromosomes, but it is possible that it may be connected with the transference of nucleolar substance to the nuclear thread.
In the yeast cell the nucleus is represented by a homogenous granule, probably of a nucleolar nature, surrounded and perhaps to some extent impregnated by chromatin and closely connected with a vacuole which often has chromatin at its periphery, and contains one or more volutin granules which appear to consist of nucleic acid in combination with an unknown base.
Nucleolar components involved in ribosome biogenesis cycle between the nucleolus and nucleoplasm in interphase cells.