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In cases of known Rh incompatibility, the mother is given an injection of RhoGAM, an immune globulin preparation, at about 28 weeks of pregnancy and again immediately after the child's birth.
Such treatments are vaccine or immune globulin for hepatitis A, typhoid, meningitis, Japanese encephalitis, and rabies.
If the blood test is positive, the baby should receive vaccine along with hepatitis B immune globulin (HBIG) at birth.
Sometimes, corticosteroids or immune globulin may be given to improve platelet production.