Worried
disturbed, agitated, grieved, apprehensive, pained, anxious, perplexed, afflicted, confused, puzzled, in a quandary, upwrought, overwrought, chagrined, bothered, harassed, vexed, plagued, teased, annoyed, concerned, uneasy, discomposed, disquieted, harried, careworn, mortified, badgered, baited, inconvenienced, put out, upset, flurried, flustered, afflicted, bored, tortured, piqued, pricked, goaded, irritated, displeased, exacerbated, tried, roused, disconcerted, pursued, fretted, chafed, galled, rubbed the wrong way, discommoded, ragged, tired, unquiet, molested, crossed, thwarted, fashed, fazed, distressed, wounded, sickened, griped, irascible, restless, irked, pestered, heckled, beset, persecuted, frightened, alarmed, terrified, scared, anguished, harrowed, tormented, provoked, stung, nettled, ruffled, fretting, perturbed, afraid, shaky, fearful, unsettled, suspicious, in turmoil, full of misgivings, shaken, careworn, dreading, bugged*, between the devil and the deep blue sea*, in a stew*, on pins and needles*, all hot and bothered*, worried stiff*, in a tizzy*, burned up*, discombobulated*, miffed*, peeved*, all in a dither*, riled*, aggravated*, with ants in one's pants*, behind the eight ball*, floored*, up a tree*, hung-up*, up the creek without a paddle*, uptight*, on the anxious seat*; see also doubtful 2.
Antonyms calm*, at ease, settled.