This service is to be extended further with an adolescent clinic at UCLH where 4-6 patients including osteogenesis imperfecta will be seen.
Specific diseases causing an increased risk for fractures include Paget's disease, rickets, osteogenesis imperfecta, osteoporosis, bone cancer and tumors, and prolonged disuse of a nonfunctional body part such as after a stroke.
Osteogenesis imperfecta-An inherited disorder of the connective tissues that involves multiple symptoms, including weakened bones that break easily.
Osteogenesis imperfecta (OI) is a group of genetic diseases in which the bones are formed improperly, making them fragile and prone to breaking.
In osteogenesis imperfecta, the collagen produced is abnormal and disorganized, which results in a number of abnormalities throughout the body, the most notable being fragile, easily broken bones.