Beneath the epidermis is a thin cutis, which is followed by the muscular layers (external circular and internal longitudinal).
In addition to diffuse pigment (mostly in the epidermis), the skin contains granular pigment stored up r' in cells, the chromatophores, restricted to the cutis, which are highly mobile and send out r2 branches which, by contraction and expansion, may rapidly alter the coloration, most batrachians being in this respect quite comparable to the famous chameleons.
Systemic corticosteroids have caused deposition of calcium in the skin (calcinosis cutis ).
