The greatest philologist of antiquity was, however, his successor, Aristophanes of Byzantium (195), who reduced accentuation and punctuation to a definite system, and used a variety of critical symbols in his recension of the Iliad and Odyssey.
Its deposition seems to have followed a time of deformation which resulted in an increase of altitude in the Appalachian Mountains, and in an accentuation of the contrast between the highlands and the adjacent plains.
This arrangement still survives in some of the ancient churches of Rome; it has been revived in many Protestant places of worship. It symbolized principally an official distinction; but with the theocratizing of the empire in the East and its decay in the West the accentuation of the mystic powers of the clergy led to a more complete separation from the laity, a tendency which left its mark on the arrangements of the churches.
The wave of change (nervous impulse) induced in a neuron by advent of a stimulus is after all only a sudden augmentation of an activity continuous within the neuron - a transient accentuation of one (the disintegrative) phase of the metabolism inherent in and inseparable from its life.