See unbalance in Webster's New World Roget's A-Z Thesaurus II
verb
To make insane:
craze, derange, madden, unhinge. See sane
noun
Serious mental illness or disorder impairing a person's capacity to function normally and safely:
brainsickness, craziness, dementia, derangement, disturbance, insaneness, insanity, lunacy, madness, mental illness, psychopathy. (Psychiatry) mania. (Psychology) aberration, alienation. See sane
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