The interval of secession was perhaps the happiest in his life.
On the 10th of January 1861 an ordinance of secession, which declared Florida to be a " sovereign and independent nation," was adopted by a state convention, and Florida became one of the Confederate States of America.
He repudiated the doctrine of secession, and pleaded for compromise and conciliation.
Newman's secession in 1845 placed Manning in a position of greater responsibility, as one of the High Church leaders, along with Pusey and Keble and Marriott; but it was with Gladstone and James Hope (afterwards Hope-Scott) that he was at this time most closely associated.
In 1865 President Johnson appointed as provisional governor William Lewis Sharkey (1797-1873), who had been chief justice of the state in 1832-1850, and a convention which assembled on the 14th of August recognized the "destruction" of slavery and declared the ordinance of secession null and void.