To keep in operation
manipulate, conduct, administer; see command 2,
manage 1.
To be in operation
function, work, serve, carry on, run, revolve, act, behave,
fulfill, turn, roll, spin, pump, lift, spark, explode, burn,
move, progress, advance, proceed, go, contact, hit, engage,
transport, convey, contain, exert, click*, tick*,
percolate*; see also perform 1.
Antonyms stop*, stall, break down.
To produce an effect
react, act on, influence, bring about, determine, turn, bend,
contrive, work, accomplish, fulfill, finish, complete, benefit,
compel, promote, concern, enforce, take effect, have effect,
work on, succeed, get results*, get across*, turn
the trick*; see also achieve 1, produce
1.
To carry out a surgical procedure
excise, cut, remove diseased tissue, amputate, transplant an
organ, set a bone, explore, carve up*; see also
treat 3.