Synonyms for disorganize

put out of order, disarrange, disorder, upset, disrupt, derange, break up, disperse, destroy, scatter, litter, clutter, break down, deprive of organization, dislocate, demobilize, disband, jumble, muddle, mislay, misplace, embroil, unsettle, disturb, perturb, shuffle, toss, throw into disorder, throw into confusion, turn topsy-turvy*, complicate, confound, overthrow, overturn, stampede, agitate, disarray, dishevel, scramble, mix up, mess up*; see also confuse.

Antonyms systematize*, order, arrange.